خلاصة:
Introduction: Pancreatic -cells function and insulin sensitivity resistance were impaired in type 2 diabetes. The effect of lifestyle activity modification (LAM) on these parameters is unclear. The aim of present study was to examine the effect of 8 weeks LAM on pancreatic -cells
function and insulin resistance in middle aged men with insulin resistance.
Material & Methods: Sixteen obese and overweight middle aged men (age, 35-50 years) with insulin resistance participated in this study. The subjects were randomly assigned to LAM group (n=8) or control group (n=8). The subjects in LAM group walked 2 miles in 30 minutes on a treadmill on 4 days per week for 12 weeks according to the guidelines of the Centers for Disease Control and Prevention and American College of Sports Medicine.Results: The results indicated that fasting blood sugar, fasting insulin and insulin resistance index decreased and pancreatic -cells function increased significantly after the intervention. Conclusion: In summary, it seems that LAM improves
insulin resistance and pancreatic -cells function in obese men with insulin resistance.
ملخص الجهاز:
Effects of lifestyle activity modification on insulin resistance and pancreatic-cells function in obese men with insulin resistance Mohadeseh Nematollahzadeh Mahani1* and Jalil Ghasemianpoor1 Received: 22 May 2018 / Accepted: 4 August 2018 (1) The General Department of Fars Province Education (*) MS in Exercise Physiology, Education Administration in Shiraz; E.
com Abstract Introduction: Pancreatic β-cells function and insulin sensitivity resistance were impaired in type 2 diabetes.
Recently, Omidi and Moghadasi (2017) reported that 8 weeks aerobic training with 60-75% of maximum heart rate improves insulin resistance but it had not effective on pancreatic β-cells function in female patients with type 2 diabetes (17).
The present study evaluated the effects of LAM training, suggested exercise program by CDC and ACSM, without diet control in sedentary middle- aged men who were overweight or obese.
The major finding of the present study is that 12 weeks LAM alone can improve insulin resistance in addition to the improvement in pancreatic β-cell function and decrease in body mass and body fat percent, suggesting that this intervention is effective to induce glucose homeostasis in obese men.
5. Conclusion LAM training, suggested exercise program by CDC and ACSM, can improve insulin resistance in addition to the improvement in pancreatic β-cell function and decrease in body mass and body fat percent, suggesting that this intervention is effective to induce glucose homeostasis in obese men.
Regular aerobic training improves insulin resistance but not pancreatic β-cells function in female patients with type 2 diabetes.