High-intensity interval training improves blood pressure and adropin plasma levels in elderly with hypertensive treatment مقالة

Adropin is a newly identified bioactive protein that is important in energy hemostasis and vascular endothelial function. The purpose of the present study was to investigate plasma levels of adropin and nitrite/nitrate (NO), in elderly treated hypertensive subjects at baseline and follow-up after 6 weeks of high-intensity interval training (HIIT).forty-four elderly treated hypertensives were divided into HIIT and control groups. The HIIT group intervention was 10 intervals (1.5 min) at 85% to 90% heart rate reserve (HRR) separated by 2 min at 50% to 55% HRR in 3 session per week for 6 weeks. Plasma levels of adropin and NO were measured by enzyme-linked immunosorbent assay. After 6- week HIIT plasma levels of adropin and NO were significantly increased compared to control and baseline (PΔ adropin in the HIIT group showed a positive correlation with increased Δ NO (r= 0.707, P= 0.002) and Δ VO2peak (r= 0.836, P= 0.001).The results indicate that HIIT increased plasma levels of adropin may contribute, in part, to blood pressure reduction by increasing nitric oxide production.