چکیده:
Introduction: Leptin, a protein with a cytokine-like helical structure and molecular weight of 16 KDa, regulates the body weight and homeostasis of the energy in the body. The aim of this study was to investigate the response of plasma leptin and some of selected hormones to one session of progressive running in non- athlete males.Material and Methods: Twenty three male (age 19.58 ± 2.12 yr, BMI 21.63 ± 2.7 kg/m2 and weight 64.86 ±6.46 kg) performed a session of exhausting session running at 60-85% maximal heart rate. Blood samples were taken before and immediately after exhausting exercise to measure of plasma leptin, insulin, cortisol, lactate and glucose.Results: results of this study indicated that one progressive running session decreased plasma leptin but thisdecrease was not significant (P=0/42). Also there was a significant decrease in plasma insulin (P=0/009) and glucose (P=0/03) but no significant decrease was observed in cortisol levels. But significant increase was observed in lactate concentration (P=0/0001).Discussion and Conclusion: We have concluded that, lack of a significant decrease in leptin concentrations were due to low energy expenditure during of acute exercise. The result of this study and other research suggest that for the leptin concentration to decrease, exercise must be at least as long as than 60 minutes with an energy expenditure of about 800 kcal in non- athletes.
خلاصه ماشینی:
"The aim of this study was to investigate the response of plasma leptin and some of selected hormones to one session of progressive running in non- athlete males.
The result of this study and other research suggest that for the leptin concentration to decrease, exercise must be at least as long as than 60 minutes with an energy expenditure of about 800 kcal in non- athletes.
Therefore the purpose of this study was to investigate the response of plasma leptin and some selected hormones to one progressive running session in non-athlete males.
Table 1: Anthropometric and physiological characteristics of study participants (mean ± SD) (رجوع شود به تصویر صفحه) Experimental design According to research plan schedule, one week before the exhaustion exercise, anthropometric and physiological factors including weight, body mass index and maximal oxygen consumption were measured.
05) Table 2: Mean and SD of plasma Leptin, lactate, Insulin, glucose and cortisol on pre and post (رجوع شود به تصویر صفحه) Discussion and Conclusion Investigation of leptin response to exercise has been investigated in many studies.
In consistent with our findings, Sari (2007), Zolandz (2005), Hilton (2000), Vatansever (2011) have also reported no significant change in plasma leptin levels after exercise [17-20].
According to the findings of this study and other similar research in this area [12], exercise longer than 60 minutes with energy expenditure higher than 800 kcal can be recommended for the reduction of leptin concentration in non-athletes.
Acute effect of exercise on plasma leptin level and insulin resistance in obese women with stable caloric intake."