چکیده:
Objective: The aim of this study was to investigate the prevalence and its determinants of Antipsychotic Use in patients with psychiatric disorders. Materials and Methods: This study was on patients with psychiatric disorder that have discharged from the hospital. We have assessed all patients with psychiatric interview and evaluation of their psychiatric documentations. Results: 90.7% of all of patients had taken antipsychotic medications and antipsychotic polypharmacy was in 27.2% of these patients. The most prevalent component of antipsychotic polypharmacy was consisting of Chlorpromazine, Halopreidol and Chlorpromazine, Risperidone and then Chlorpromazine, Olanzapine respectively. There were significant relations between pattern of antipsychotic use and gender, occupation status, type of psychiatric ward, duration of hospitalization and cost of treatment but no relationship with age, educational status and duration of illness. Conclusion: This study suggests that prevalence of antipsychotic polypharmacy is high in in-patient psychiatric patients.
خلاصه ماشینی:
There were significant relations between pattern of antipsychotic use and gender, occupation status, type of psychiatric ward, duration of hospitalization and cost of treatment but no relationship with age, educational status and duration of illness.
Poly therapy was observed in male, older subjects, hospitalization condition, and higher doses of equivalent chlorpromazine, longer period of illness, added consumption of anticholinergic and less consumption of atypical drugs.
(22) In a descriptive study for prevalence evaluation of poly pharmacy in treatment and educational hospitals (2005), relevance was found to be 39% and 28%, respectively.
(40) According to considerable prevalence of psychotic disorders, wide consumption of antipsychotic drugs, possible side effects of these drugs, and high medication cost, we conducted a study to determine the pattern of psychotic drugs consumption and their dependent variables in educational and treatment wards of Razi Psychiatric Hospital.
Table (1) illustrates frequency distribution of the taken amount of psychiatric drugs and poly pharmacy in patients, respectively.
1 - - Total 790 100 779 100 790 100 716 100 The relationship between consumption pattern of antipsychotic drugs and variables of age, gender, job, education, illness period, hospitalization period, hospitalization ward, and medication cost of patients have been analyzed respectively.
The difference between educations of patients with antipsychotic drugs poly pharmacy was not significant.
This investigation can be a premise for further studies on changing antipsychotic drugs consumption pattern from poly pharmacy to mono therapy, for psychosis disorders.