اثر شش هفته تمرین تایچی بر سطوح سرمی BDNF،TNF-α و عملکرد شناختی و جسمانی زنان با عارضه سکته مغزی مقاله

Purpose: The aim of this study was to determine the effect of Tai Chi training on TNF-α, BDNF serum levels and cognitive and physical function in women with stroke. Methods: 20 women in Qom city with stroke (mean age: 65.80±3.55y, weight: 68.41±14.00 kg and body mass index: 26.33± 5.15kg.m2) voluntarily were divided randomly into Tai Chi group (10 patients) and control group (10 patients). Serum BDNF and TNF-α were analyzed by using an ELISA kits in pretest and post-test. Cognitive function were assessed by the Mini- Mental State Examination (MMSE). Also pretest and post-test measurements were recorded for the timed upand- go test. Tai Chi group trained 6 weeks, three times per week for 60 minutes (consisted of a 10-minutes warm-up period, 40-minutes simplified Tai Chi exercises performed, and a 10- minutes cool-down period). Data were analyzed using the independent samples t-test and paired samples t-test. Results: Tai Chi group showed a significant improvement in serum TNF-α and dynamic balance (p≤0.05). Despite the increase in serum BDNF and improvement cognitive function, no significant differences were observed between the two groups. Conclusion: Therefore the findings of this study suggest that Tai Chi training as a low intensity and simple training can improve women balance and inflammatory status with stroke.