چکیده:
Introduction: Macrophages and oxidized low-density lipoprotein (ox-LDL) have been verified playing vital roles in the pathogenesis of atherosclerosis. The role of exercise
intensity in circulating ox-LDL is not clearly understood in obesity and it is not well known which exercise intensity is needed to ox-LDL reductions in response to endurance
training. Thus the purpose of this study was to comparison the effect of regular high-intensity vs. moderate-intensity exercise on ox-LDL in obese men.
Material & Methods: Twenty four sedentary obese men (aged: 41.0 ± 5.9 years and BMI: 31.1 ± 3.4 kg/m2; ± SD) volunteered to participate in this study. The subjects were
randomly assigned to moderate-intensity exercise (MIE) group (n=8), high-intensity exercise (HIE) group (n=8) or control group (n=8). The subjects in MIE group walked 2
miles in 30 minutes on a treadmill on 4 days per week for 12 weeks according to the guidelines of the Centers for Disease Control and Prevention and American College of Sports
Medicine; however, the subjects in the HIE group performed 2 M. Nematollahzadeh Mahani
endurance training 4 days a week for 12 weeks at an intensity corresponding to 75-80% individual heart rate reserve (HRR) for 45 min. Results: The results showed that total cholesterol (TC), triglycerides (TG) and LDL were decreased and HDL increased after MIE and HIE (P<0.05). ox-LDL
concentration was decreased only after HIE. For TC and HDL significant differences were observed between MIE group and HIE group (P<0.05). Conclusions: The results suggest that although lipid profile of obese men improves after regular moderate and highintensity
exercise, ox-LDL levels decreases only after regular high-intensity exercise.
خلاصه ماشینی:
Effect of regular exercise with different intensities on oxidized LDL levels in obese men Mohadeseh Nematollahzadeh Mahani * Received: 2 June 2018 / Accepted: 11 August 2018 (*) MS in Exercise Physiology, Education Administration in Shiraz; E.
The subjects in MIE group walked 2 miles in 30 minutes on a treadmill on 4 days per week for 12 weeks according to the guidelines of the Centers for Disease Control and Prevention and American College of Sports Medicine; however, the subjects in the HIE group performed1 endurance training 4 days a week for 12 weeks at an intensity corresponding to 75-80% individual heart rate reserve (HRR) for 45 min.
Results: The results showed that total cholesterol (TC), triglycerides (TG) and LDL were decreased and HDL increased after MIE and HIE (P Keywords: Intensity of exercise, Obesity, Oxidative stress, Lipid profile, ox-LDL 1.
Some recent cross-sectional and longitudinal studies recently report that plasma concentrations of circulating ox-LDL are directly associated with body mass index (BMI), waist circumstance, obesity, weight loss, and physical fitness (11).
(2009) indicated that ox-LDL concentration is reduces after 10 weeks endurance exercise with 66% of heart rate reserve (HRR) in old sedentary men and women but it had not significant changes after 10 weeks endurance exercise with 33% of HRR (13).
Furthermore, 12-week healthy-life exercise program with 50-70% of HRR has been reported to decrease ox-LDL concentrations in obese elderly women (14).
Furthermore, 12-week healthy-life exercise program with 50-70% of HRR has been reported to decrease ox-LDL concentrations in obese elderly women (14).