Abstract:
Intrudaction: PYY (3-36) has an important role in satiety; reduce food intake and regulation of energy homeostasis. The aim of this study was to determine the small intestine and kidney PYY (3-36) relative gene expression in response to treadmill-running training in female rats.Material and Methods: Twenty female wistarrats (6-8 weeks oldand 125-135 g weight) were used. Animalswere randomly assigned into saline-control (SC), saline-training (ST), and Baneh-control (BC), and Baneh- training (BT). Training groups were given exercise on a motor-driven treadmill at 25 m/min (0% grade) for 60 min/dayand5 days/week for eight weeks. Subjects were fed orally, withBaneh extraction and saline for four weeks. PYY (3-36) relative gene expression was detected by Real-time PCR method.Results: Results demonstrated that Baneh extraction significantly increases PYY (3-36) relative geneexpression in small intestine (P < 0.013) and kidney (P < 0.025).Also exercise reduces PYY (3-36) relative gene expression in and kidney (P < 0.03).Discussion and Conclusion: Exercise training decreases PYY (3-36) relative gene expression in smallintestine and kidney
Machine summary:
"The aim of this study was to determine the small intestine and kidney PYY (3-36) relative gene expression in response to treadmill-running training in female rats.
Discussion and Conclusion: Exercise training decreases PYY (3-36) relative gene expression in smallintestine and kidney Key Words: PYY (3-36), Female rats, Treadmill exercise, Pistachio atlantica Introduction There is, a complex physiological system called homeostasisin humans in whichthebalance between energy intake and energy expenditure is created [1].
(رجوع شود به تصویر صفحه) Figure1: Real-time PCR of small intestine PYY (3-36) relative mRNA expression in saline-control (SC), saline- training (ST), Baneh-control (BC), and Baneh-training (BT) wild-type female rats.
031) (رجوع شود به تصویر صفحه) Figure2: Real-time PCR of Kidney PYY (3-36) relative mRNA expression in saline-control (SC), saline-training (ST), Baneh-control (BC), and Baneh-training (BT) wild-type female rats.
03) Discussion and Conclusion To our knowledge, this is the first report to demonstrate alterations of female rat small intestine and kidney PYY (3-36)relative gene expression in response to a treadmill running and Baneh crud extraction regime.
The major finding of the present study wasthe observation of a higher PYY (3- 36)relative gene expression in control groups of small intestine and kidney than trained groups.
The important point of this research was the significant increase of PYY (3-36) gene expression by Baneh in small intestine and kidney that was probably due to high levels of fatty acid in the Baneh (Figures 1, 2).
In conclusion, the present study showed a significantly lowerrelative expression of PYY (3- 36) mRNA in small intestine and kidney following treadmill running program in female rats."