Abstract:
Introduction: Necdin is an important negative regulator of
white adipogenesis. The acute effect of aerobic exercise on
necdin concentration is unclear; therefore the present study
was conducted to determine the effects of a bout of intensive
aerobic exercise on necdin concentration in obese and lean
men.
Material & Methods: Eighteen sedentary obese (Age: 21.7 ±
2.1 and BMI: 33.7 ± 2.1 kg/m2; ± SD, n = 9) and lean (Age:
20.5 ± 0.7 and BMI: 17.6 ± 1.6 kg/m2; ± SD, n = 9) men
volunteered to participate in this study. All the subjects were
performed the Bruce test as the intensive aerobic exercise.
Blood samples were taken before and immediately after the
intensive aerobic exercise.
Results: No significant differences were observed at baseline
in necdin concentration between obese and lean subjects (35.8 ± 24.2 vs. 21.9 ± 16.2 pg/ml; P = 0.2 respectively).
After an intensive aerobic exercise necdin concentration
increased significantly in the lean subjects (21.9 ± 16.2 to
65.9 ± 86.1 pg/ml; P = 0.01) however no significant changes
were observed in the obese subjects (35.8 ± 24.2 to 36.9 ±
19.3 pg/ml; P = 0.5). The results revealed that necdin
concentration was higher in the lean subjects in compare to
the obese subjects (P = 0.03) in response to a bout of
intensive aerobic exercise.
Conclusion: The results of present study suggest that necdin
concentration increases in response to acute aerobic exercise
in lean subjects. Future studies are needed to examine the
effect of exercise training on necdin levels in the obese
subjects.
Machine summary:
Changes of necdin concentration after a bout of intensive aerobic exercise in obese and lean men Ahmad Ahmadlu1*, Afsaneh Khazari2 and Zahra Momen Nasab2 Received: 15 March 2019/ Accepted: 10 May 2019 (1)* PhD in Exercise physiology, Education Administration in Shiraz.
Conclusion: The results of present study suggest that necdin concentration increases in response to acute aerobic exercise in lean subjects.
The acute effect of aerobic exercise on necdin concentration is unclear; therefore the present study was conducted to determine the effects of a bout of intensive aerobic exercise on necdin concentration in obese and lean men.
The acute effect of aerobic exercise on necdin concentration is unclear; therefore the present study was conducted to determine the effects of a bout of intensive aerobic exercise on necdin concentration in obese and lean men.
Anthropometric and body composition parameters (mean ± SD) of the subjects {مراجعه شود به فایل جدول الحاقی} * P Changes of necdin concentration in response to intensive aerobic exercise in the obese and lean subjects are presented in the Figure 1.
The aim of present study was to determine the effects of a bout of intensive aerobic exercise on necdin concentration in obese and lean men.
Surprising, the results of present study indicated that there are no significant differences in necdin concentration between obese and lean subjects.
The results of the present study revealed that necdin concentration increased significantly in the lean subjects after a bout of intensive aerobic exercise; however no significant changes were observed in the obese subjects.